I find I have a standardised approach to workflow but every now and then I play around with the camera profile settings. In the main I use Adobe standard when using ACR and when I use DPP I use Camera standard. A few years ago I always used Camera standard in ACR but I was persuaded that Adobe was likely to be more accurate or realistic. I attach three images that were processed using my standard approach using the same raw file so I have not set out to make one image any better or worse than another. I have not done anything in Photoshop other than sharpen. I deliberately did not retouch the eye either. They were all sharpened using the same regime and the images were all cropped to the same size prior to sharpening. The only difference between the images is the raw conversion. Do you see a significant difference, which one do you prefer. I won't say any more or ask further questions as I do not wish to introduce any bias.
Image order is B, A, C