Of course. I have used nothing else for the last three years. I love the color. And the simplicity. Especially when you save a recipe for each camera/ISO combo with all of your recommended settings.... For the 5DS R I have been using your 5D III NR values. I need to get you some 5DS R raw files. I worked an ISO 3200 5DS R image this morning and it looked pretty good... Folks can learn about our DPP 4 RAW Conversion Guide
here.
Here is a technical question for you: should it theoretically be more difficult to make sharp images with this camera rather than with previous Canon bodies because of the pixel pitch?